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Displaying items by tag: Research

Scientists Have Identified More Than 200 Genetic Markers Linked to Baldness
A new study has pinpointed over 200 new gene variations linked to baldness. This is a huge step forward as previously only eight markers had been identified. This is good news for those who show signs of balding. These new finding will help doctors and researchers to better understand baldness and learn how to prevent it in the future. It will enable them to pinpoint specific target areas to research.

The 287 gene variations were located on over 100 different specific genes. Many of the genes relate to hair development and structure. Most of the newly found genetic variations were located near genes that had been previously identified as relating to hair growth and development. Many of the genes associated with balding are located on the X chromosome, which is inherited from the mother. The most well-known gene marker is related to the androgen receptor. It is related to the binding of testosterone and is known to be a major marker related to balding.

Over 52,000 men participated in this study. Most of them ranged in age from 40 to 70 years old. The participants were equally split between those that showed signs of balding and those that did not. Based on their findings, scientists created an algorithm to help determine who could potentially develop hair loss. Both men and women can use the algorithm to determine if they are at risk for gene-related baldness. Researchers are also attempting to determine if other factors such as waist-to-height ratio and age of menarche could be used to discern early onset balding. Essentially, there is an increased awareness between the overlap of other genetic factors and balding.

Another important factor in the early identification of baldness is that some individuals who are at risk for balding are also at risk for other harmful diseases, such as prostate cancer and cardiovascular disease. These studies are preliminary. However, with early detection, they can be addressed in a timely manner. If you score higher on the algorithm and are at risk for balding, you could also take preventive measures for cardiovascular disease.

The study presents new opportunities for further research. There is the potential to develop new products based on the findings. Researchers’ aim is to reduce or predict balding in both men and women in the future. With so many new discoveries, the chances of finding the root cause or causes are hopeful.

REPORT: Researchers Grow Fully Functional Skin (With Hair!)

Skin can do a lot of things, but one thing it can do especially well is simply grow. Every month our body fully replaces its skin, and there are close to 19 million skin cells an inch! But in the lab, this has been difficult to repeat. However, recently, some Japanese scientists grew functional skin tissue, and they were able to transplant it onto living organisms.

This technique has only been tested on mice. However, in the future, it could change things for victims of burns or for people who have undergone skin damage of a catastrophic nature. And also, less severely perhaps, this skin growth could be used to treat male pattern baldness, which many men experience as they get older.

The researchers in Japan who worked with mice to create skin were able to implant it into the gums of mice to build clusters, some of which looked like a growing embryo. They chose mice that had a fully functioning immune system, just to make sure that they would accept the transplant. This is a huge step forward.

As skin is one of the largest--and most important--organs in the body, it's also difficult to treat it well when it's been damaged. So far, they've come up with skin grafts (which can be painful) and artificial skin (which is far from ideal). The skin grown in the lab shows that this new skin can be made with hair follicles and sweat glands, enabling it to stay moisturized and control temperatures.

Now, this can help with skin repair, but it can also help with baldness. After the mice received the skin implants, they began growing hair, which shows that the skin implanted is capable of doing the same for a person, too. It's perfectly possible that this type of skin implant could be used to aid men who have male-pattern baldness, and this is not too far off in the future.

While the technique is still about 5 or 10 years off, relatively speaking, that's not too far away. But since 95 percent of men and 50 percent of women suffer from baldness at some point, this is something that is likely to be popular when it is made public.

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Wednesday, 06 April 2016 19:00

SM04554 A Hopeful Cure for Baldness

Here Is What We Know About SM04554SM04554 for hair loss

There is new hope that a cure for baldness is on the horizon. Apparently, this new drug can reverse hair loss, and this promise gives hope to millions. The drug is produced by the company Samumed, and they have completed a trial of this new drug. The drug is called SM04554, and shows promise in treating male pattern baldness.

About 35 million men in the US have male pattern baldness to contend with as they get older. This drug was tested on 302 men between the ages of 18 and 15, according to the medical research company, and this new drug was quickly found to increase hair count and also to increase hair density in men who are balding.

This brings promise for so many, for many men look in the mirror and see only that they are losing their hair. And in the past 15 years, there are only two drugs that have been approved to treat male pattern baldness. Now, with the introduction of SM04554, Samumed tells us that change is in the air.

The new drug works by opening up signaling pathways in the body's cells, and the SM04554 is actually a small molecule compound that does so quickly and with great luck, initiating and maintaining the growth of hair where other drugs in the past may have failed to do so.

After the 135 day trial, the men in the study showed great increases in hair growth and density. The trial looked at the hair of 302 men, and they were split up into three groups. One group received a placebo, one group received a 0.15 percent solution, and another group received a 0.25 percent solution.

These 302 men took the drug for 90 days at a rate of once a day, and they had a follow-up 45 days later. The men who took the solutions were found to have greater hair growth and greater hair density than those men who took the placebo. Apparently, the drug was found to be helpful and useful on all accounts. All that's needed is further research into the possibilities for curing male-pattern baldness.  If all goes as planned SM04554 could be available in the next four to five years.

Can't Wait 5 Years for SM04554?

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Monday, 07 December 2015 18:00

Caffeine Can Halt Hair Loss

Caffeine Can halt hair lossCaffeine Can halt hair loss, says German scientist

Caffeine has long been known as a stimulant. However, it is able to perk up more than just you after a long day of work or as you drag throughout the long afternoon hours. Many facial skin products include caffeine in order to help give that nice, natural, chemical boost to your skin and help perk it up. Shouldn't there be other elements to your body that are able to respond to the natural elements of caffeine?

According to German scientists, it can. Hair loss is mostly based on genetics, but there are ways to slow it down and even stop it. As the hair follicles begin to thin and slow down in production, what many of these follicles need is a bump of energy to boost production and to halt the slow down. If what the German researchers have to say is true, caffeine might just be the perfect, natural ingredient to do this for you.

There are a few different ingredients that are known to help stimulate the body. One is niacin. This is a B-vitamin. It is used to increase energy and to offer individuals a burst of endurance. In fact, the German researchers first looked at how athletes would use the elements found in caffeine for doping means. They believed that if the drug could be used to artificially enhance a person's body to improve athletic performances, it should be able to boost hair and its ability to grow.

The hair is a tissue/organ that has a very high energy demand. It, along with nails, requires a significant amount of energy to grow. It is why hair and nails are often the first elements of a person's body to suffer when they are not absorbing enough nutrients and energy during the day. The German researches pointed out that the roots of hair require 10 times the amount of energy to grow during the growth period than during the resting period (all hair grows in phases, as some hair follicles lay dormant for months at a time. So, the research look towards including caffeine into the root system of the head in order to add this necessary energy to the hair roots.

The growth is a long term process as it does take a while for the roots to begin to show the increased energy from the roots. This includes a continual development and connection with the caffeine, which takes around six to eight months.