A new study has pinpointed over 200 new gene variations linked to baldness. This is a huge step forward as previously only eight markers had been identified. This is good news for those who show signs of balding. These new finding will help doctors and researchers to better understand baldness and learn how to prevent it in the future. It will enable them to pinpoint specific target areas to research.
The 287 gene variations were located on over 100 different specific genes. Many of the genes relate to hair development and structure. Most of the newly found genetic variations were located near genes that had been previously identified as relating to hair growth and development. Many of the genes associated with balding are located on the X chromosome, which is inherited from the mother. The most well-known gene marker is related to the androgen receptor. It is related to the binding of testosterone and is known to be a major marker related to balding.
Over 52,000 men participated in this study. Most of them ranged in age from 40 to 70 years old. The participants were equally split between those that showed signs of balding and those that did not. Based on their findings, scientists created an algorithm to help determine who could potentially develop hair loss. Both men and women can use the algorithm to determine if they are at risk for gene-related baldness. Researchers are also attempting to determine if other factors such as waist-to-height ratio and age of menarche could be used to discern early onset balding. Essentially, there is an increased awareness between the overlap of other genetic factors and balding.
Another important factor in the early identification of baldness is that some individuals who are at risk for balding are also at risk for other harmful diseases, such as prostate cancer and cardiovascular disease. These studies are preliminary. However, with early detection, they can be addressed in a timely manner. If you score higher on the algorithm and are at risk for balding, you could also take preventive measures for cardiovascular disease.
The study presents new opportunities for further research. There is the potential to develop new products based on the findings. Researchers’ aim is to reduce or predict balding in both men and women in the future. With so many new discoveries, the chances of finding the root cause or causes are hopeful.